KLOW Blend 80mg (GHK-Cu, KPV, BPC-157, TB-500)

The KLOW blend vial holds 50mg of GHK-Cu, 10mg of KPV, 10mg of BPC-157 and 10mg of TB-500, freeze-dried together for 80mg altogether. It’s meant for lab and analytical work only.

KLOW blend certificate of analysis

Every KLOW blend batch we list has a Freedom Diagnostics report behind it. The lab measures purity by HPLC and confirms identity by mass spectrometry, and you can open the full reports in the photo gallery on this page.

• Klow 80mg: 99.385% purity, reported 2/28/2026, search code ONYX2602270067
• KLOW 80mg: 99.66% purity, reported 8/13/2025, search code onyx2508120022

The highest result on file is 99.66%. Each report carries a search code, so you can look it up on the Freedom Diagnostics website and check that it matches what’s shown here.

The compounds in KLOW blend

GHK-Cu is the tripeptide glycyl-L-histidyl-L-lysine bound to a copper(II) ion. Loren Pickart first isolated GHK from human plasma in 1973, and levels in plasma are reported to fall with age.

KPV is the tripeptide lysine-proline-valine, the C-terminal end of alpha-melanocyte stimulating hormone. It keeps alpha-MSH’s anti-inflammatory activity without the pigment effects.

BPC-157 is a 15-amino-acid peptide based on a fragment of body protection compound, a protein first found in gastric juice. It’s one of the most widely studied research peptides, almost entirely in rodents.

TB-500: Thymosin beta-4 is a 43-amino-acid protein found in nearly every cell, where it binds actin and helps control cell movement. TB-500 is the name used for synthetic thymosin beta-4 and for a short fragment of its active region.

KLOW is the GLOW formula plus 10mg of KPV. KPV brings the inflammatory side of repair to GHK-Cu’s remodeling and the BPC-157 and TB-500 pair, which makes it the widest repair blend we sell.

The ratio is locked in at manufacture. One vial, one mix, the same proportion every time. For custom ratios, use the single-compound vials.

Mechanisms in the blend

GHK binds copper tightly and can deliver it to cells. Copper is a cofactor for lysyl oxidase, the enzyme that cross-links collagen and elastin, and for antioxidant enzymes.

Alpha-MSH calms inflammation through melanocortin receptors. KPV is its last three amino acids and keeps much of that anti-inflammatory activity.

Nobody has pinned down a single receptor for BPC-157. Lab studies point to several pathways: it raises VEGF receptor expression, which feeds blood vessel growth, it interacts with the nitric oxide system, and it increases growth hormone receptor levels in tendon cells.

Thymosin beta-4’s main job is holding on to G-actin, the building block of the cell’s internal scaffolding. By controlling how much actin is free to polymerize, it controls how cells move and change shape.

KLOW blend at a glance

• GHK-Cu: CAS 49557-75-7
• KPV: CAS 67727-97-3, C16H30N4O4, 342.4 g/mol
• BPC-157: CAS 137525-51-0, C62H98N16O22, 1,419.5 g/mol
• TB-500 (thymosin beta-4): CAS 77591-33-4, C212H350N56O78S, 4,963.4 g/mol
• Amount per vial: 80mg (50mg + 10mg + 10mg + 10mg)
• Form: lyophilized (freeze-dried) powder in a crimp-sealed glass vial
• SKU: ONYX-KLOW-80
• Use: laboratory research only

Research findings

Maquart and colleagues reported in 1988 that GHK-Cu stimulated collagen synthesis in cultured fibroblasts, and later rat wound-chamber studies found more collagen and glycosaminoglycan buildup.

Dalmasso and colleagues reported in Gastroenterology (2008) that KPV reduced inflammation in mouse colitis models and was taken up through PepT1.

Most of the work comes from Predrag Sikiric’s group at the University of Zagreb. Their rodent studies report faster healing of tendon, ligament, muscle and gut injuries, and Mikus and colleagues described improved burn wound healing in mice.

Goldstein and colleagues reviewed thymosin beta-4’s role in wound repair in 2012, covering faster closure of skin wounds and new blood vessel growth in animal models.

To read the studies yourself, open this PubMed search at the U.S. National Library of Medicine.

Checking your vials

Start with the label: Onyx Research, the compound name and the amount should all match what you ordered. Then look at the seal. The crimp should be tight with no cracks in the glass.

Freeze-dried powder often shakes loose in transit. Loose powder is no problem if it’s dry. Droplets on the glass or a shrunken, glassy film mean moisture got in, and we’ll want to hear about it.

Write the arrival date on the box, and add the mixing date and volume later. That short log answers most questions if a result looks odd.

Reconstitution chart and steps

Pick your water volume first and the strength follows from it. With the 80mg vial:

• Add 2mL: 40mg/mL (4,000mcg per 0.1mL, or 10 units on a U-100 syringe)
• Add 3mL: 26.67mg/mL (2,666.7mcg per 0.1mL, or 10 units on a U-100 syringe)
• Add 5mL: 16mg/mL (1,600mcg per 0.1mL, or 10 units on a U-100 syringe)

Give a cold vial five minutes on the bench, then swab the top. Let the bacteriostatic water trickle down the side and roll the vial gently between your palms. It should turn clear within a minute or two.

Storage and stability

Sealed KLOW blend lasts longest frozen at -20°C and dark. The fridge is fine for short spells. Mixed solution stays at 2 to 8°C and should be used within roughly 28 days.

Let a frozen vial come up to room temperature before you open it, or condensation forms on the powder.

Often bought with it

• GHK-Cu Copper Peptide, a copper peptide
• GLOW Blend 70mg (GHK-Cu, BPC-157, TB-500): GHK-Cu, BPC-157 and TB-500 in one vial
• Melanotan 2 (MT-2), a melanocortin agonist
• TB-500 10mg, a thymosin beta-4 peptide
• Wolverine Blend 10mg (BPC-157 and TB-500): BPC-157 and TB-500 in one vial

For more options, open our skin and tanning peptides and healing peptides or head back to the Onyx Research home page.

KLOW blend FAQ

How much is in a KLOW blend vial?

80mg in total: 50mg + 10mg + 10mg + 10mg.

How does ordering work?

Add it to the cart with anything else you need, then check out. Everything ships together.

Is there a lab report?

Yes. The certificate of analysis is in the product photos, and the purity results are listed on this page.

Which diluent should I use?

Bacteriostatic water in most cases. Our mixing chart above shows the concentration for 1, 2 or 3mL.

Is there a crypto discount?

Yes. Pay with cryptocurrency at checkout and an extra discount comes off your order.

Order KLOW blend online

KLOW blend is in stock at $120.00. Add it to the cart, and your order ships free, wherever you are.

Paying with crypto? Choose it at checkout for an extra discount on the whole order.

Building a larger order? See what else is in our skin and tanning peptides and healing peptides.

Research use only. Onyx Research supplies this material to qualified labs for in-vitro work. It’s not a medicine, supplement, food or cosmetic, and it must not be given to people or animals. No statement here has been reviewed by the FDA.