Epitalon 10mg (Epithalon)

Epitalon comes as 10mg of freeze-dried Epithalon in a crimp-sealed glass vial. In short, it’s a synthetic tetrapeptide. It’s meant for lab and analytical work only.

Epitalon purity and COA

Freedom Diagnostics, an independent US lab, tested Epitalon for Onyx Research using HPLC-UV for purity and mass spectrometry for identity. The certificate sits in the gallery next to the vial photos.

• Epithalon 10mg: 99.571% purity, reported 1/26/2026, search code Onyx2601230044

Our labels promise 99% purity, and the reports above come in at up to 99.571%. Enter the search code on the Freedom Diagnostics site to pull up the same report yourself.

Epithalon (Epitalon) background

Epithalon (also spelled Epitalon) is the synthetic tetrapeptide Ala-Glu-Asp-Gly. Vladimir Khavinson’s group in St. Petersburg designed it from the amino acid makeup of epithalamin, an extract of the pineal gland.

It’s the best known of the Khavinson bioregulator peptides and is studied mainly for telomere biology and aging.

Mechanism of action

Epitalon is modeled on epithalamin, a peptide extract of the pineal gland. The pineal gland produces melatonin, and the original work looked at how it changed with age.

In cell culture, Khavinson’s group reported that epitalon switched on telomerase, the enzyme that rebuilds the protective caps on chromosome ends. Its other reported effects include normalizing melatonin rhythms in older animals.

Epitalon details

• Compound: Epithalon (Epitalon)
• Also known as: Epitalon, AEDG
• CAS number: 307297-39-8
• Molecular formula: C14H22N4O9
• Molecular weight: 390.3 g/mol
• Structure: Ala-Glu-Asp-Gly
• Amount per vial: 10mg
• Form: lyophilized (freeze-dried) powder in a crimp-sealed glass vial
• SKU: ONYX-EPI-10
• Use: laboratory research only

What the research reports

Khavinson and colleagues reported in 2003 that Epithalon switched on telomerase and lengthened telomeres in cultured human fibroblasts.

Studies from the same institute reported longer lifespans and fewer tumors in some strains of mice and rats. Most of this work comes from one group, so independent replication is still limited.

You can read the original papers through this PubMed search for Epithalon, a free database from the U.S. National Library of Medicine.

How Epithalon compares

Short version: Epithalon is the four-amino-acid peptide studied for telomerase and the pineal gland. Labs often weigh it against these:

• NAD+ is the coenzyme every cell needs for energy reactions and sirtuin activity

Each one targets a different process tied to aging: telomeres, cell energy, oxidative stress, senescent cells or the thymus. Every one of them is in stock in our anti-aging peptides.

Epitalon dilution chart

These figures use the 10mg vial. For a bigger vial, multiply by the size difference.

• Add 1mL: 10mg/mL (1,000mcg per 0.1mL, or 10 units on a U-100 syringe)
• Add 2mL: 5mg/mL (500mcg per 0.1mL, or 10 units on a U-100 syringe)
• Add 3mL: 3.33mg/mL (333.3mcg per 0.1mL, or 10 units on a U-100 syringe)

Use bacteriostatic water, added slowly down the inside of the vial. Swirl, don’t shake. If some powder sticks to the glass, rest the vial in the fridge for a few minutes and swirl again.

Storage and stability

Put sealed Epitalon vials in the freezer at -20°C if you won’t use them soon. A few days on a shelf during transit does no harm to dry powder. Once you’ve added water, the vial lives in the fridge at 2 to 8°C for up to about four weeks.

Let a frozen vial come up to room temperature before you open it, or condensation forms on the powder.

What to check on delivery

Each vial carries the black and white Onyx Research label with the compound, the amount, 99% purity and the research-use line. Check that the name and amount match your order and that the cap and crimp are tight.

The powder should look dry and pale, either as a solid cake or loose granules. If the cake has crumbled in the box, that’s expected. Powder that looks wet, gummy or off-color is not, so keep that vial out of use and send us a photo.

Write the arrival date on the box, and add the mixing date and volume later. That short log answers most questions if a result looks odd.

More anti-aging peptides

• MOTS-c 10mg, a mitochondrial peptide
• NAD+ 500mg, a coenzyme
• GHK-Cu Copper Peptide, a copper peptide
• GLP-2 TZ 10mg (Tirzepatide), a GIP/GLP-1 agonist
• GLP-1 SM 10mg (Semaglutide), a GLP-1 agonist

For more options, open our anti-aging peptides or head back to the Onyx Research home page.

Frequently asked questions

How much is in a Epitalon vial?

10mg, as printed on the label.

Is it in stock?

Yes, Epitalon is in stock today.

Is there a crypto discount?

Yes. Pay with cryptocurrency at checkout and an extra discount comes off your order.

Do you charge for shipping?

Shipping is free on all orders, wherever you are.

How does ordering work?

Add it to the cart with anything else you need, then check out. Everything ships together.

Buy Epitalon from Onyx Research

Order Epitalon now from $55.00. It’s in stock, and shipping is free on every order.

Paying with crypto? Choose it at checkout for an extra discount on the whole order.

Building a larger order? See what else is in our anti-aging peptides.

Research use only. Onyx Research supplies this material to qualified labs for in-vitro work. It’s not a medicine, supplement, food or cosmetic, and it must not be given to people or animals. No statement here has been reviewed by the FDA.